The Role of Pharmacology in Geriatric Medicine.

Abstract

Pharmacology plays a pivotal role in geriatric medicine by addressing the complex needs of an aging population. Older adults often experience physiological changes, comorbidities, and polypharmacy, which significantly influence drug absorption, distribution, metabolism, and excretion. These factors increase their vulnerability to adverse drug reactions (ADRs), drug interactions, and therapeutic inefficacy. Geriatric pharmacology focuses on optimizing medication use through individualized therapy, careful dose adjustments, and comprehensive monitoring. This review highlights the principles of pharmacology in older adults, emphasizing the importance of personalized treatment plans, deprescribing, and interdisciplinary approaches to improve patient outcomes and safety.