Pharmacology in Pediatrics: Dosing and Safety Considerations

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Zohoor Hassan Zughaibi, Naif Zunayqit Ruddah Alkhaldi, Bandar Nazzal Al Azmi, Awadh Musleh Alrakah, Yusra Ata Abdulqader, Abdullah Saad Al-Baqmi, Qasem Khaled Lafi Aljarari, Awad Salem Ali Alshamrani, Ali Mohammad Yahia Jaafari, Ahmed Mays Hurayyis Alruwaili, Moath Abdullah Aljared, Ali Mesfer Salem Al Mutlaq, Fawaz Baqiyyah Almutairi, Hassan Ahmed Ali Al Mesham, Khalid Ibrahim Abdullah Alzahrani

Abstract

Pharmacology in pediatrics involves the study of how medications affect children, considering their unique developmental physiology. Children are not simply small adults; they experience significant developmental changes that affect drug absorption, distribution, metabolism, and excretion. Consequently, pediatric pharmacology requires careful attention to drug dosing, safety, and efficacy to prevent adverse outcomes. This review explores key considerations in pediatric pharmacology, focusing on age-based dosing, weight-based dosing, the role of body surface area in drug calculation, and the importance of drug safety in pediatric populations. Understanding these principles is crucial for optimizing therapeutic interventions in children.

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