A Review on Calcium Nanoparticles (Canps): Green Synthesis, Characterization Methods and Potential Therapeutic Action Against Post-Menopausal Osteoporosis Complications

Abstract

Women are more susceptible to osteoporosis because of the substantial loss of bone strength brought on by the absence of ovarian estrogen after menopause. Many different treatment strategies are being tried to fight the war against osteoporosis have been tested. The discipline of nanotechnology has proven to be one of the most dynamic areas of study. Its applications appear to be one of the most innovative and promising technologies in biology, requiring more research for the creation of novel materials in the nanometric range. Various inorganic nanoparticles have been investigated to induce cytotoxicity in cancer cells and one of the successfully tried nanoparticles is selenium nanoparticles (CaNPs). Green synthesized of SeNPs are a promising source of new antioxidant and anti-inflammatory agents, given Calcium nanoparticles have been extensively studied as drug carriers. They have been investigated as gene therapy delivery vehicles, bone drug delivery, bone regeneration, enamel repair, and intracellular protein carriers. This is why calcium nanoparticles have attracted growing interest in nanomedicine owing to their excellent biocompatibility and strong biodegradability which can be an alternative to classical medicines with greater effectiveness and in a shorter period.